HERBAL MEDICINES OR DIETARY SUPPLEMENTS AND RIMONABANT
The manufacturers predict that potent inducers of CYP3A4 such as St John's wort (Hypericum perforatum) may lower the serum levels of rimonabant. This is based on the fact that potent inhibitors of CYP3A4 increase rimonabant levels.
Caution is recommended with concurrent use of St John's wort and rimonabant. Patients should be monitored to ensure rimonabant remains effective.
Caution is recommended with concurrent use of St John's wort and rimonabant. Patients should be monitored to ensure rimonabant remains effective.