HERBAL MEDICINES OR DIETARY SUPPLEMENTS AND TRICYCLICS
The plasma levels of amitriptyline can be reduced by St John's wort (Hypericum perforatum) and nortriptyline seems to be similarly affected. Other tricyclics are also expected to interact.
Both the tricyclics and St John's wort are antidepressants, but whether the final sum of this interaction is more or less antidepressant activity is not known. Monitor antidepressant efficacy if St John's wort is given with any tricyclic.
Both the tricyclics and St John's wort are antidepressants, but whether the final sum of this interaction is more or less antidepressant activity is not known. Monitor antidepressant efficacy if St John's wort is given with any tricyclic.