HERBAL MEDICINES OR DIETARY SUPPLEMENTS AND TRIPTANS
The CSM in the UK noted that pharmacodynamic interactions have been identified between triptans and St John's wort (Hypericum perforatum) leading to an increased risk of adverse effects. This has been seen with other drugs with serotonergic effects, such as the SSRIs.
The CSM suggest that patients taking triptans should not take St John's wort preparations: the manufacturers generally advise caution, which seems prudent, see serotonin syndrome.
The CSM suggest that patients taking triptans should not take St John's wort preparations: the manufacturers generally advise caution, which seems prudent, see serotonin syndrome.