
HRT AND WARFARIN AND OTHER ORAL ANTICOAGULANTS
A report describes a woman who needed more acenocoumarol when her HRT treatment with oral conjugated oestrogens was changed to transdermal estradiol. A retrospective analysis of women starting HRT found that three needed warfarin dose increases of about 10 to 30%.
Direct information is limited. Note that, because of the increased risk of developing venous thromboembolism with HRT, the use of HRT in women already on anticoagulant therapy requires careful consideration of the risks and benefits. If the combination is used be aware that the anticoagulant response may be affected.
Direct information is limited. Note that, because of the increased risk of developing venous thromboembolism with HRT, the use of HRT in women already on anticoagulant therapy requires careful consideration of the risks and benefits. If the combination is used be aware that the anticoagulant response may be affected.