ISONIAZID AND THEOPHYLLINE
Two short-term studies found that theophylline serum levels were slightly increased by isoniazid and a case of theophylline toxicity supports this finding. However,
another short-term study found that isoniazid slightly increased theophylline clearance.
The outcome of concurrent use is uncertain but it would be prudent to be alert for any evidence of increased theophylline levels and toxicity if isoniazid is given. It may take 3 to 4 weeks for this interaction to develop.
another short-term study found that isoniazid slightly increased theophylline clearance.
The outcome of concurrent use is uncertain but it would be prudent to be alert for any evidence of increased theophylline levels and toxicity if isoniazid is given. It may take 3 to 4 weeks for this interaction to develop.