LAMOTRIGINE AND RIFAMPICIN (RIFAMPIN)
Rifampicin increases the clearance of lamotrigine and reduces its AUC by 97% and 44%, respectively. A lamotrigine dose increase was required in one case report.
Information is limited but rifampicin could reduce the efficacy of lamotrigine. Monitor the patient and increase the lamotrigine dose if required.
Information is limited but rifampicin could reduce the efficacy of lamotrigine. Monitor the patient and increase the lamotrigine dose if required.