LEFLUNOMIDE AND RIFAMPICIN (RIFAMPIN)
Rifampicin increases the levels of the active metabolite of leflunomide (A771726) by 40%.
There would seem to be no reason for avoiding concurrent use, but the manufacturers advise caution as levels may build up over time. It may be prudent to increase the frequency of leflunomide monitoring if these two drugs are used together.
There would seem to be no reason for avoiding concurrent use, but the manufacturers advise caution as levels may build up over time. It may be prudent to increase the frequency of leflunomide monitoring if these two drugs are used together.