LEFLUNOMIDE AND WARFARIN AND OTHER ORAL ANTICOAGULANTS
Leflunomide appears to raise the INR of patients taking warfarin. Case reports describe bleeding, and INRs as high as 6 and 11.
It would seem prudent to closely monitor the INR of any patient taking warfarin who is started on leflunomide.
It would seem prudent to closely monitor the INR of any patient taking warfarin who is started on leflunomide.