
LEVODOPA AND PHENYTOIN
The therapeutic effects of levodopa can be reduced by phenytoin.
Evidence is limited (effects in 5 patients only). If concurrent use is necessary be aware that some patients may experience a worsening of symptoms. It seems possible that fosphenytoin, a prodrug of phenytoin, could have similar effects.
Evidence is limited (effects in 5 patients only). If concurrent use is necessary be aware that some patients may experience a worsening of symptoms. It seems possible that fosphenytoin, a prodrug of phenytoin, could have similar effects.