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LEVODOPA AND SSRIS

Medical Diagnosis and Drugs, Medications
The use of an SSRI is often beneficial in patients with Parkinson's disease taking levodopa. However, sometimes parkinsonian symptoms are worsened.
Although the information is limited, it seems that in some cases parkinsonism can be worsened by SSRIs. Concurrent use is valuable and need not be avoided, but monitor the outcome and withdraw the SSRI if necessary.
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