LEVOTHYROXINE AND SEVELAMER
Sevelamer decreases levothyroxine absorption and appears to increase levothyroxine requirements.
It would be prudent to monitor levothyroxine requirements in patients requiring sevelamer. Whether separation of administration would minimise any interaction remains to be demonstrated, but, where absorption is a problem, the manufac- turers generally recommend avoiding giving other drugs at least 1 hour before or 3 hours after sevelamer.
It would be prudent to monitor levothyroxine requirements in patients requiring sevelamer. Whether separation of administration would minimise any interaction remains to be demonstrated, but, where absorption is a problem, the manufac- turers generally recommend avoiding giving other drugs at least 1 hour before or 3 hours after sevelamer.