LITHIUM AND METHYLDOPA
Symptoms of lithium toxicity, not always associated with raised lithium levels, have been described in 4 patients and 4 healthy subjects when they were also given methyldopa.
Avoid concurrent use whenever possible, but if concurrent use is essential the effects should be closely monitored. Serum lithium monitoring may be unreliable because symptoms of toxicity can occur even though the levels remain within the normally accepted therapeutic range.
Avoid concurrent use whenever possible, but if concurrent use is essential the effects should be closely monitored. Serum lithium monitoring may be unreliable because symptoms of toxicity can occur even though the levels remain within the normally accepted therapeutic range.