
LITHIUM AND SSRIS
The concurrent use of lithium and SSRIs can be advantageous and uneventful, but various kinds of neurotoxicities have occurred. Isolated reports describe the develop- ment of symptoms similar to those of serotonin syndrome in patients taking lithium with fluoxetine, fluvoxamine, paroxetine and possibly citalopram. In addition, fluoxetine appears to have caused increases and decreases in serum lithium levels.
If lithium is used with an SSRI be alert for any evidence of toxicity. If these symptoms occur treatment should be withdrawn.
If lithium is used with an SSRI be alert for any evidence of toxicity. If these symptoms occur treatment should be withdrawn.