
MACROLIDES AND RIMONABANT
Ketoconazole doubles the AUC of rimonabant. Other drugs that are potent inhibitors of CYP3A4, such as clarithromycin and telithromycin, are predicted to interact similarly. Note that the macrolides differ in their ability to inhibit CYP3A4, see macrolides.
The manufacturers of rimonabant recommend caution. Monitor for signs of
increased rimonabant adverse effects.
The manufacturers of rimonabant recommend caution. Monitor for signs of
increased rimonabant adverse effects.