MACROLIDES AND STATINS - OTHER STATINS
No interaction of note would be expected between fluvastatin, pravastatin or rosuvastatin and macrolides.
Although no interaction would generally be expected to occur note that there have been case reports of rhabdomyolysis in patients taking statin/macrolide combinations that have been predicted not to interact. Any patient taking a statin should be advised to look out for symptoms of myopathy (e.g. muscle pain or weakness). It may be prudent to reinforce this when macrolides are given.
Although no interaction would generally be expected to occur note that there have been case reports of rhabdomyolysis in patients taking statin/macrolide combinations that have been predicted not to interact. Any patient taking a statin should be advised to look out for symptoms of myopathy (e.g. muscle pain or weakness). It may be prudent to reinforce this when macrolides are given.