MACROLIDES AND STATINS - SIMVASTATIN OR LOVASTATIN
The levels of simvastatin and lovastatin are increased by clarithromycin, erythromy- cin, telithromycin and other macrolides that inhibit CYP3A4 (see macrolides). Rhabdomyolysis has been seen.
It has been recommended that simvastatin and lovastatin should be stopped during short courses of these macrolides.
It has been recommended that simvastatin and lovastatin should be stopped during short courses of these macrolides.