MAOIS AND VENLAFAXINE
Serious and potentially life-threatening reactions ( serotonin syndrome) can develop if venlafaxine and non-selective, irreversible MAOIs are given concurrently, or even sequentially if insufficient time is left in between.
The manufacturers of venlafaxine recommend that one week should elapse between stopping the venlafaxine and starting an MAOI, and 2 weeks between stopping an MAOI and starting venlafaxine.
The manufacturers of venlafaxine recommend that one week should elapse between stopping the venlafaxine and starting an MAOI, and 2 weeks between stopping an MAOI and starting venlafaxine.