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MEBENDAZOLE AND PHENOBARBITAL

Medical Diagnosis and Drugs, Medications
Carbamazepine lowers the plasma levels of mebendazole. Phenobarbital and primidone are expected to interact similarly.
When treating systemic worm infections it may be necessary to increase the mebendazole dosage in patients taking phenobarbital or primidone. Monitor the outcome of concurrent use. This interaction is of no importance when mebendazole is used for intestinal worm infections where its action is a local effect on the worms in the gut.
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