METRONIDAZOLE (FLAGYL)
Metronidazole (Flagyl); Antibacterial; Cap: 375 mg
Cream: 0.75% [45 gm], 1% [30, 45 gm]
Gel: 0.75% [30, 45 gm]
Inj: 500 mg
Lotion: 0.75% [60 mL]
Tab: 250, 500 mg
Tab ER: 750 mg; Anaerobic infections: 30 mg/kg/day PO/ IV q6-8h (max 4 gm/ day).
Clostridium difficile: 20-35 mg/kg/day PO/IV q6h (max 4 gm/ day). Oral route is preferred.
Amebiasis: 35-50 mg/kg/day PO tid (max 2250 mg/day)
Other parasitic infections: 15-30 mg/kg/day PO tid (max 750 mg/day).
Helicobacter: 15-20 mg/kg/day PO bid x 4 weeks (max 1500 mg/day) with amoxicillin and bismuth subsalicylate
Topical: Apply to affected area bid.
Reduce dosage in hepatic failure. Avoid alcohol due to risk of disulfiram-like reaction. May cause metallic taste.
Extemporaneously prepared suspension may be made from the tablets with 30-day stability under refrigeration.
Cream: 0.75% [45 gm], 1% [30, 45 gm]
Gel: 0.75% [30, 45 gm]
Inj: 500 mg
Lotion: 0.75% [60 mL]
Tab: 250, 500 mg
Tab ER: 750 mg; Anaerobic infections: 30 mg/kg/day PO/ IV q6-8h (max 4 gm/ day).
Clostridium difficile: 20-35 mg/kg/day PO/IV q6h (max 4 gm/ day). Oral route is preferred.
Amebiasis: 35-50 mg/kg/day PO tid (max 2250 mg/day)
Other parasitic infections: 15-30 mg/kg/day PO tid (max 750 mg/day).
Helicobacter: 15-20 mg/kg/day PO bid x 4 weeks (max 1500 mg/day) with amoxicillin and bismuth subsalicylate
Topical: Apply to affected area bid.
Reduce dosage in hepatic failure. Avoid alcohol due to risk of disulfiram-like reaction. May cause metallic taste.
Extemporaneously prepared suspension may be made from the tablets with 30-day stability under refrigeration.