MODAFINIL AND PHENYTOIN
There is some in vitro evidence to indicate that modafinil may possibly inhibit the metabolism of phenytoin. Fosphenytoin, a prodrug of phenytoin, may interact similarly.
It may be prudent to monitor the effects of phenytoin in the presence of
modafinil, taking levels if any evidence of toxicity occurs (e.g. blurred vision, nystagmus, ataxia or drowsiness).
It may be prudent to monitor the effects of phenytoin in the presence of
modafinil, taking levels if any evidence of toxicity occurs (e.g. blurred vision, nystagmus, ataxia or drowsiness).