NASAL DECONGESTANTS AND SIBUTRAMINE

There do not appear to be any studies on the use of sibutramine with decongestants, cough and cold medications, but the manufacturers predict that a rise in blood pressure or heart rate could occur. Ephedrine, phenylpropanolamine, pseudoephe- drine, and xylometazoline (all indirect-acting sympathomimetics) have been specif- ically named.
Avoid concurrent use where possible. If both drugs are given monitor the outcome closely.