NNRTIS AND RIFABUTIN - EFAVIRENZ
Rifabutin does not affect efavirenz levels, but efavirenz may decrease rifabutin levels.
The US Center for Disease Control and Prevention states that the combination is probably clinically useful, and they suggest increasing the dose of rifabutin to 450 mg or 600 mg daily, or 600 mg two to three times weekly. Monitor the outcome of concurrent use carefully.
The US Center for Disease Control and Prevention states that the combination is probably clinically useful, and they suggest increasing the dose of rifabutin to 450 mg or 600 mg daily, or 600 mg two to three times weekly. Monitor the outcome of concurrent use carefully.