NSAIDS AND OPIOIDS - NSAIDS, GENERAL

On the whole the concurrent use of NSAIDs and opioids is successful and without incident. The following specifically studied pairs have not been found to interact adversely: alfentanil with parecoxib, codeine with diclofenac, dextropropoxyphene (propoxyphene) with meclofenamate, dextropropoxyphene (propoxyphene) with sulindac, fentanyl with parecoxib, methadone with intramuscular diclofenac, and morphine with ketoprofen. There seems no reason to assume other NSAIDs and opioids will interact. However, see the specific instances discussed below.
No action needed.