NSAIDS AND TACROLIMUS
The UK manufacturers of tacrolimus suggest that all NSAIDs may have additive nephrotoxic effects with tacrolimus. Cases of renal failure have been reported in patients receiving the combination.
Tacrolimus levels and/or effects (e.g. on renal function) should be monitored as a matter of routine, but it may be prudent to increase monitoring if NSAIDs are started.
Tacrolimus levels and/or effects (e.g. on renal function) should be monitored as a matter of routine, but it may be prudent to increase monitoring if NSAIDs are started.