NSAIDS AND WARFARIN AND OTHER ORAL ANTICOAGULANTS - OTHER NSAIDS
Case reports suggest that most NSAIDs can occasionally enhance the effects of warfarin and other coumarins (acenocoumarol, phenprocoumon), resulting in increased anticoagulant effects and sometimes severe bleeding events.
Monitor the anticoagulant effect if NSAIDs are added to or withdrawn from the treatment of patients taking anticoagulants. Note that since NSAIDs reduce platelet aggregation and cause gastrointestinal irritation they can prolong and worsen any bleeding events.
Monitor the anticoagulant effect if NSAIDs are added to or withdrawn from the treatment of patients taking anticoagulants. Note that since NSAIDs reduce platelet aggregation and cause gastrointestinal irritation they can prolong and worsen any bleeding events.