OPIOIDS AND SSRIS - TRAMADOL
Several case reports describe the development of serotonin syndrome, in patients taking fluoxetine, paroxetine or sertraline with tramadol. Another patient developed hallucinations when taking tramadol with paroxetine.
There would seem to be little reason for totally avoiding the concurrent use of the SSRIs and tramadol but it would clearly be prudent to use the combination cautiously and monitor the outcome closely. Tramadol should be used with caution with SSRIs because of the possible increased risk of seizures.
There would seem to be little reason for totally avoiding the concurrent use of the SSRIs and tramadol but it would clearly be prudent to use the combination cautiously and monitor the outcome closely. Tramadol should be used with caution with SSRIs because of the possible increased risk of seizures.