PHENOBARBITAL AND QUINIDINE
Quinidine levels can be reduced by the concurrent use of phenobarbital or primidone. Loss of arrhythmia control is possible if the quinidine dosage is not increased.
Concurrent use need not be avoided, but be alert for the need to increase the quinidine dosage. If phenobarbital or primidone are withdrawn the quinidine dosage may need to be reduced to avoid quinidine toxicity. Quinidine serum levels should be monitored if possible.
Concurrent use need not be avoided, but be alert for the need to increase the quinidine dosage. If phenobarbital or primidone are withdrawn the quinidine dosage may need to be reduced to avoid quinidine toxicity. Quinidine serum levels should be monitored if possible.