PHENOBARBITAL AND TETRACYCLINES
The serum levels of doxycycline are reduced and may fall below the accepted minimum inhibitory concentration in patients receiving long-term treatment with barbiturates.
It has been suggested that the doxycycline dosage could be doubled. Alternatively, tetracycline, oxytetracycline, and chlortetracycline appear not to interact and may therefore be suitable alternatives.
It has been suggested that the doxycycline dosage could be doubled. Alternatively, tetracycline, oxytetracycline, and chlortetracycline appear not to interact and may therefore be suitable alternatives.