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PROBENECID AND QUINOLONES

Medical Diagnosis and Drugs, Medications
Probenecid increases the serum levels and/or decreases the urinary excretion of cinoxacin, ciprofloxacin, clinafloxacin, enoxacin, fleroxacin, levofloxacin, nalidixic acid and norfloxacin.
This is unlikely to be of clinical significance unless other drugs that affect renal
clearance are taken concurrently. Grepafloxacin, moxifloxacin, sparfloxacin, and probably ofloxacin, appear not to interact with probenecid.
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