PROTEASE INHIBITORS AND SIROLIMUS
Nelfinavir increased the levels of sirolimus in one patient. Other protease inhibitors
are predicted to raise sirolimus levels.
Sirolimus levels and effects (e.g. on renal function) should be monitored as a
matter of routine, but it would be prudent to increase monitoring if protease
inhibitors are given.
are predicted to raise sirolimus levels.
Sirolimus levels and effects (e.g. on renal function) should be monitored as a
matter of routine, but it would be prudent to increase monitoring if protease
inhibitors are given.