PROTEASE INHIBITORS AND TRICYCLICS
Ritonavir raises desipramine levels and is predicted to also raise the levels of other tricyclic antidepressants. In vitro evidence suggests that other protease inhibitors may interact similarly, but to a lesser extent.
A lower starting dose of desipramine has been suggested, and monitoring is advisable if tricyclic antidepressants are given to patients taking protease inhibitors.
A lower starting dose of desipramine has been suggested, and monitoring is advisable if tricyclic antidepressants are given to patients taking protease inhibitors.