PYRIMETHAMINE (DARAPRIM)
Pyrimethamine (Daraprim); Antimalarial; Tab, scored: 25 mg; Toxoplasmosis treatment:
2 mg/kg/day PO q12h x 3 days then 1 mg/kg/day PO qd-bid x 4 weeks (max 25 mg/day)
Give with sulfadiazine and folic acid. Administer with meals to avoid vomiting.
Extemporaneous suspension can be made with 3 months stability under refrigeration or at room temperature.
Rabies immune globulin (Hyperab, Imogam); Immune Globulin; Inj: 150 IU/mL; 20 IU/kg (0.133 mL/kg). Use up to half the dose to infiltrate the wound
site. Administer the balance of the dose IM at a different site.
Not to be given IV. Also give rabies vaccine if bitten.
Rabies Vaccine (Imovax, RabAvert); Vaccine; Inj: > 2.5 IU of whole virus rabies antigen; Administer IM x 5 doses after exposure - now and in 3, 7, 14,
and 28 days post exposure.
2 mg/kg/day PO q12h x 3 days then 1 mg/kg/day PO qd-bid x 4 weeks (max 25 mg/day)
Give with sulfadiazine and folic acid. Administer with meals to avoid vomiting.
Extemporaneous suspension can be made with 3 months stability under refrigeration or at room temperature.
Rabies immune globulin (Hyperab, Imogam); Immune Globulin; Inj: 150 IU/mL; 20 IU/kg (0.133 mL/kg). Use up to half the dose to infiltrate the wound
site. Administer the balance of the dose IM at a different site.
Not to be given IV. Also give rabies vaccine if bitten.
Rabies Vaccine (Imovax, RabAvert); Vaccine; Inj: > 2.5 IU of whole virus rabies antigen; Administer IM x 5 doses after exposure - now and in 3, 7, 14,
and 28 days post exposure.