RIFABUTIN AND TACROLIMUS
Rifampicin (rifampin) increases the clearance and decreases the bioavailability of tacrolimus. Rifabutin is expected to interact similarly, although to a lesser extent.
Tacrolimus levels and effects (e.g. on renal function) should be monitored as a matter of routine, but it is advisable to increase monitoring if rifabutin is started or stopped.
Tacrolimus levels and effects (e.g. on renal function) should be monitored as a matter of routine, but it is advisable to increase monitoring if rifabutin is started or stopped.