RIFAMPICIN (RIFAMPIN) AND TRIMETHOPRIM
Rifampicin reduces the AUC of trimethoprim (given as co-trimoxazole) by 56% in HIV- positive subjects, but apparently has no effect on trimethoprim in healthy subjects.
The interaction between rifampicin and trimethoprim seems unlikely to be relevant in subjects who are not infected with HIV. Consider also co-trimoxazole.
The interaction between rifampicin and trimethoprim seems unlikely to be relevant in subjects who are not infected with HIV. Consider also co-trimoxazole.