THEOPHYLLINE AND VACCINES
BCG vaccine appears to slightly increase the half-life of theophylline. Normally influenza vaccines (whole-virion, split-virion and surface antigen) do not interact with theophylline, but raised theophylline levels and toxicity have been seen in occasional cases.
It seems possible that the occasional patient may develop some signs of theophylline toxicity, especially if their serum levels are already towards the top end of the therapeutic range, but most patients are unlikely to be affected.
It seems possible that the occasional patient may develop some signs of theophylline toxicity, especially if their serum levels are already towards the top end of the therapeutic range, but most patients are unlikely to be affected.